› 1agg

Solution NMR

THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA

Released:
DOI: 10.2210/pdb1agg/pdb
PDB entry 1agg coloured by chain, ensemble of 24 models, front view.
PDB entry 1agg coloured by chain, ensemble of 24 models, side view.
PDB entry 1agg coloured by chain, ensemble of 24 models, top view.
Source organism: Agelenopsis aperta
Primary publication:
The solution structure of omega-Aga-IVB, a P-type calcium channel antagonist from venom of the funnel web spider, Agelenopsis aperta.
Reily MD, Thanabal V, Adams ME
J. Biomol. NMR 5 122-32 (1995)
PMID: 7703698

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153335 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Omega-agatoxin-Aa4b Chain: A
Molecule details ›
Chain: A
Length: 48 amino acids
Theoretical weight: 5.29 KDa
Source organism: Agelenopsis aperta
UniProt:
  • Canonical: P37045 (Residues: 36-83; Coverage: 76%)
Sequence domains: Spider toxin
Structure domains: Omega-AgatoxinV

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores

Quick links

Citations

8 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
7 more

2 mentions without citation

Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Buczek et al. (2007)
1 more