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EBI PDBe PDBeView

PDBe Entry: 1aeg view

SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (4-AMINOPYRIDINE)
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.1 Å, Spacegroup: P 21 21 21
Released 04/09/1997, deposition: 24/02/1997, last revision: 24/02/2009
Authors Musah, R.A.search; Jensen, G.M.search; Fitzgerald, M.M.search; Mcree, D.E.search; Goodin, D.B.search
Primary citation Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.MOL.BIOL.search vol:315, pag:845-857 (2002) [PubMed ID 11812152 ]search
Keywords OXIDOREDUCTASEsearch, PEROXIDASEsearch, TRANSIT PEPTIDEsearch
EC 1.11.1.5 ExPASy BRENDA search (A)
Organism Saccharomyces cerevisiae(baker's yeast) 4932search(A)
UniProt Cytochrome c peroxidase, mitochondrial precursor (EC 1.11.1.5) (CCP) P00431search (A)
Solvent A
Polymers
Id Name Type UniProt Residues Observed
A CYTOCHROME C PEROXIDASE Protein P00431 (CCPR_YEAST)search
 294 98%
Heterogens
Id Name Ligands
A PROTOPORPHYRIN IX CONTAINING FE HEM search
A 4-AMINOPYRIDINE 4AP search
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