1aby Summary

pdbe.org/1aby
spacer

CYANOMET RHB1.1 (RECOMBINANT HEMOGLOBIN)

The structure was published by Kroeger, K.S. and Kundrot, C.E., in 1997 in a paper entitled "Structures of a hemoglobin-based blood substitute: insights into the function of allosteric proteins." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 1997.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely HEMOGLOBIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HEMOGLOBIN P69905 (1-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B HEMOGLOBIN P68871 (3-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D HEMOGLOBIN P68871 (3-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (1 - 142) HEMOGLOBIN Homo sapiens
P68871 (3 - 147) HEMOGLOBIN Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P69905) oxygen transportsearch bicarbonate transportsearch protein heterooligomerizationsearch response to hydrogen peroxidesearch transportsearch oxidation-reduction processsearch small molecule metabolic processsearch hydrogen peroxide catabolic processsearch positive regulation of cell deathsearch extracellular regionsearch cytosolsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch membranesearch extracellular vesicular exosomesearch cytosolic small ribosomal subunitsearch blood microparticlesearch endocytic vesicle lumensearch haptoglobin bindingsearch peroxidase activitysearch protein bindingsearch oxygen bindingsearch metal ion bindingsearch oxygen transporter activitysearch iron ion bindingsearch heme bindingsearch
B, D (P68871) small molecule metabolic processsearch positive regulation of nitric oxide biosynthetic processsearch bicarbonate transportsearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch renal absorptionsearch oxidation-reduction processsearch oxygen transportsearch blood coagulationsearch nitric oxide transportsearch platelet aggregationsearch response to hydrogen peroxidesearch transportsearch regulation of blood vessel sizesearch protein heterooligomerizationsearch regulation of blood pressuresearch hemoglobin complexsearch cytosolsearch endocytic vesicle lumensearch extracellular vesicular exosomesearch haptoglobin-hemoglobin complexsearch extracellular regionsearch blood microparticlesearch oxygen transporter activitysearch oxygen bindingsearch hemoglobin bindingsearch protein bindingsearch heme bindingsearch metal ion bindingsearch haptoglobin bindingsearch peroxidase activitysearch iron ion bindingsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch