1ab2 Summary

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THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL

The structure was published by Overduin, M., Rios, C.B., Mayer, B.J., Baltimore, D., and Cowburn, D., in 1992 in a paper entitled "Three-dimensional solution structure of the src homology 2 domain of c-abl." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1993.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of C-ABL TYROSINE KINASE SH2 DOMAIN. This molecule has the UniProt identifier P00519 (ABL1_HUMAN)search. The sample contained 109 residues which is < 90% of the natural sequence. Out of 109 residues 109 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A C-ABL TYROSINE KINASE SH2 DOMAIN P00519 (120-220) (ABL1_HUMAN)search Homo sapienssearch < 90% 109 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00519 (120 - 220) C-ABL TYROSINE KINASE SH2 DOMAIN Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH2 domainsearch SHC Adaptor Proteinsearch SH2 domainsearch
Chain InterPro annotation
A SH2 domainsearch