1a95 Summary

pdbe.org/1a95
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XPRTASE FROM E. COLI COMPLEXED WITH MG:CPRPP AND GUANINE

The structure was published by Vos, S., Parry, R.J., Burns, M.R., de Jersey, J., and Martin, J.L., in 1998 in a paper entitled "Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE P0A9M5 (1-152) (XGPT_ECOLI)search Escherichia coli K-12search 97% 152 98%
B XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE P0A9M5 (1-152) (XGPT_ECOLI)search Escherichia coli K-12search 97% 152 98%
C XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE P0A9M5 (1-152) (XGPT_ECOLI)search Escherichia coli K-12search 97% 152 98%
D XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE P0A9M5 (1-152) (XGPT_ECOLI)search Escherichia coli K-12search 97% 152 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0A9M5 (1 - 152) XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D (P0A9M5) Phosphoribosyltransferases (PRTases)search Rossmann foldsearch PF00156: Phosphoribosyl transferase domainsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C, D (P0A9M5) xanthine phosphoribosyltransferase activitysearch transferase activity, transferring glycosyl groupssearch metal ion bindingsearch hypoxanthine phosphoribosyltransferase activitysearch magnesium ion bindingsearch transferase activitysearch nucleoside metabolic processsearch GMP salvagesearch purine ribonucleoside salvagesearch XMP salvagesearch IMP salvagesearch plasma membranesearch membranesearch cytosolsearch

Chain InterPro annotation
A, B, C, D Phosphoribosyltransferase domainsearch Xanthine-guanine phosphoribosyltransferasesearch Phosphoribosyltransferase-likesearch