1a8m Summary details

pdbe.org/1a8m/summary_details
spacer TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT
Summary
Header LYMPHOKINEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.3 Å, R-factor: 21.8%, Free R-factor: 24.0%, Spacegroup: P 41 21 2
Released 17/06/1998, deposition: 27/03/1998, last revision: 24/02/2009
Authors Reed, C.search; Fu, Z.-Q.search; Wu, J.search; Xue, Y.-N.search; Harrison, R.W.search; Chen, M.-J.search; Weber, I.T.search
Primary citation Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2.
PROTEIN ENG.search vol:10, pag:1101-1107 (1997) [PubMed 9488135 ]search
Keywords LYMPHOKINEsearch, CYTOKINEsearch, CYTOTOXINsearch
Organism Homo sapiens(human) 9606search(A B C)
UniProt P01375search (A B C)
Solvent A, B, C
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, B, C TUMOR NECROSIS FACTOR ALPHA Protein P01375 (TNFA_HUMAN)search
157 96%
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