› 1a7p

X-ray diffraction
2.01Å resolution

FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) ENGINEERED MUTANT PRO95L->SER ON VARIANT CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL

Released:
DOI: 10.2210/pdb1a7p/pdb
PDB entry 1a7p coloured by chain, front view.
PDB entry 1a7p coloured by chain, side view.
PDB entry 1a7p coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
X-Ray Structures of D1.3 Fv Mutants
Marks C, Henrick K, Winter G
To be published

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134468 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Immunoglobulin kappa chain variable 12-41 Chain: L
Molecule details ›
Chain: L
Length: 107 amino acids
Theoretical weight: 11.68 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01635 (Residues: 21-115; Coverage: 100%)
Gene names: Gm16848, Igkv12-41
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Ig heavy chain V region PJ14 Chain: H
Molecule details ›
Chain: H
Length: 116 amino acids
Theoretical weight: 12.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01820 (Residues: 20-115; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ACY 1 x ACY
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 90.301Å b: 90.301Å c: 56.945Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.174 not available
Expression system: Escherichia coli

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