1a6y Summary



The structure was published by Zhao, Q., Khorasanizadeh, S., Miyoshi, Y., Lazar, M.A., and Rastinejad, F., in 1998 in a paper entitled "Structural elements of an orphan nuclear receptor-DNA complex." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), and ORPHAN NUCLEAR RECEPTOR NR1D1.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ORPHAN NUCLEAR RECEPTOR NR1D1 P20393 (123-216) (NR1D1_HUMAN)search Homo sapienssearch < 90% 94 89%
B ORPHAN NUCLEAR RECEPTOR NR1D1 P20393 (123-216) (NR1D1_HUMAN)search Homo sapienssearch < 90% 94 89%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P20393 (123 - 216) ORPHAN NUCLEAR RECEPTOR NR1D1 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Nuclear receptorsearch Erythroid Transcription Factor GATA-1, subunit Asearch Zinc finger, C4 type (two domains)search

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P20393) sequence-specific DNA bindingsearch zinc ion bindingsearch sequence-specific DNA binding transcription factor activitysearch regulation of transcription, DNA-templatedsearch nucleussearch

Chain InterPro annotation
A, B Zinc finger, nuclear hormone receptor-typesearch Zinc finger, NHR/GATA-typesearch