1a4s Summary

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BETAINE ALDEHYDE DEHYDROGENASE FROM COD LIVER

The structure was published by Johansson, K., El-Ahmad, M., Ramaswamy, S., Hjelmqvist, L., Jornvall, H., and Eklund, H., in 1998 in a paper entitled "Structure of betaine aldehyde dehydrogenase at 2.1 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of BETAINE ALDEHYDE DEHYDROGENASE.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A BETAINE ALDEHYDE DEHYDROGENASE P56533 (1-503) (BADH_GADMC)search Gadus morhua callariassearch 100% 503 100%
B BETAINE ALDEHYDE DEHYDROGENASE P56533 (1-503) (BADH_GADMC)search Gadus morhua callariassearch 100% 503 100%
C BETAINE ALDEHYDE DEHYDROGENASE P56533 (1-503) (BADH_GADMC)search Gadus morhua callariassearch 100% 503 100%
D BETAINE ALDEHYDE DEHYDROGENASE P56533 (1-503) (BADH_GADMC)search Gadus morhua callariassearch 100% 503 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P56533 (1 - 503) BETAINE ALDEHYDE DEHYDROGENASE Gadus morhua callarias

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D (P56533) ALDH-likesearch Aldehyde Dehydrogenase; Chain A, domain 1search, Aldehyde Dehydrogenase; Chain A, domain 2search PF00171: Aldehyde dehydrogenase familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B, C, D (P56533) metabolic processsearch oxidation-reduction processsearch glycine betaine biosynthetic process from cholinesearch oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorsearch oxidoreductase activitysearch aldehyde dehydrogenase (NAD) activitysearch betaine-aldehyde dehydrogenase activitysearch cytoplasmsearch

Chain InterPro annotation
A, B, C, D Aldehyde dehydrogenase domainsearch Aldehyde dehydrogenase, conserved sitesearch Aldehyde/histidinol dehydrogenasesearch Aldehyde dehydrogenase, N-terminalsearch Aldehyde dehydrogenase, C-terminalsearch