› 1a2d

X-ray diffraction
2.4Å resolution

PYRIDOXAMINE MODIFIED MURINE ADIPOCYTE LIPID BINDING PROTEIN

Released:
DOI: 10.2210/pdb1a2d/pdb
PDB entry 1a2d coloured by chain, front view.
PDB entry 1a2d coloured by chain, side view.
PDB entry 1a2d coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural characterization of two synthetic catalysts based on adipocyte lipid-binding protein.
Ory JJ, Mazhary A, Kuang H, Davies RR, Distefano MD, Banaszak LJ
Protein Eng 11 253-61 (1998)
PMID: 9680187

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137406 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, adipocyte Chains: A, B
Molecule details ›
Chains: A, B
Length: 131 amino acids
Theoretical weight: 14.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P04117 (Residues: 2-132; Coverage: 99%)
Gene names: Ap2, Fabp4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
1 modified residue:
Ligand PYX 2 x PYX

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P212121
Unit cell:
a: 80.08Å b: 96.25Å c: 49.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.273
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Design of functional metalloproteins.
Lu et al. (2009)
4 more

3 mentions without citation

Recognition of functional sites in protein structures.
Shulman-Peleg et al. (2004)
2 more