1a28 Summary

pdbe.org/1a28
spacer

HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN

The structure was published by Williams, S.P. and Sigler, P.B., in 1998 in a paper entitled "Atomic structure of progesterone complexed with its receptor." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of PROGESTERONE RECEPTOR.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROGESTERONE RECEPTOR P06401 (678-933) (PRGR_HUMAN)search Homo sapienssearch < 90% 256 98%
B PROGESTERONE RECEPTOR P06401 (678-933) (PRGR_HUMAN)search Homo sapienssearch < 90% 256 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06401 (678 - 933) PROGESTERONE RECEPTOR Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B Nuclear receptor ligand-binding domainsearch Retinoid X Receptorsearch Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P06401) sequence-specific DNA binding transcription factor activitysearch DNA bindingsearch steroid hormone receptor activitysearch regulation of transcription, DNA-templatedsearch steroid hormone mediated signaling pathwaysearch nucleussearch

Chain InterPro annotation
A, B Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Nuclear hormone receptor, ligand-bindingsearch