› 1zw8

Solution NMR

Solution structure of a ZAP1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb1zw8/pdb
PDB entry 1zw8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1zw8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1zw8 coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Solution structure of a Zap1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae.
Wang Z, Feng LS, Matskevich V, Venkataraman K, Parasuram P, Laity JH
J Mol Biol 357 1167-83 (2006)
PMID: 16483601

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155580 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zinc-responsive transcriptional regulator ZAP1 Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.42 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P47043 (Residues: 578-641; Coverage: 7%)
Gene names: J1145, YJL056C, ZAP1
Sequence domains:
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics combined with cartesian refinement
Expression system: Escherichia coli BL21

Quick links

Citations

12 review citations

Metalloproteins and metal sensing.
Waldron et al. (2009)
11 more

4 mentions without citation

Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain.
Hatayama et al. (2008)
3 more