Function and Biology Details
Reaction catalysed:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Peptidase S3, togavirin
- Flaviviral glycoprotein E, dimerisation domain
- Peptidase S1, PA clan, chymotrypsin-like fold
- Alphavirus E1 glycoprotein
- Peptidase S1, PA clan
- Alphavirus E2 glycoprotein
- Immunoglobulin E-set
- Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily
1 more domain
Structure domain:
Structure analysis Details
Assembly composition:
hetero 1200-mer (preferred)
Assembly name:
Capsid protein (preferred)
PDBe Complex ID:
PDB-CPX-136792 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike glycoprotein E1
Molecule details ›
Chains: A, C, E, G
Length: 290 amino acids
Theoretical weight: 31.44 KDa
Source organism: Sindbis virus
UniProt:
Length: 290 amino acids
Theoretical weight: 31.44 KDa
Source organism: Sindbis virus
UniProt:
- Canonical:
P03316 (Residues: 807-1096; Coverage: 23%)
Spike glycoprotein E1
Molecule details ›
Chains: B, D, F, H
Length: 89 amino acids
Theoretical weight: 9.45 KDa
Source organism: Sindbis virus
UniProt:
Length: 89 amino acids
Theoretical weight: 9.45 KDa
Source organism: Sindbis virus
UniProt:
- Canonical: P03316 (Residues: 1101-1189; Coverage: 7%)
Spike glycoprotein E1
Molecule details ›
Chains: I, K, M, O
Length: 31 amino acids
Theoretical weight: 3.41 KDa
Source organism: Sindbis virus
UniProt:
Length: 31 amino acids
Theoretical weight: 3.41 KDa
Source organism: Sindbis virus
UniProt:
- Canonical: P03316 (Residues: 1215-1245; Coverage: 3%)
Spike glycoprotein E2
Molecule details ›
Chains: J, L, N, P
Length: 36 amino acids
Theoretical weight: 3.75 KDa
Source organism: Sindbis virus
UniProt:
Length: 36 amino acids
Theoretical weight: 3.75 KDa
Source organism: Sindbis virus
UniProt:
- Canonical: P03316 (Residues: 691-726; Coverage: 3%)
Capsid protein
Molecule details ›
Chains: Q, R, S, T
Length: 151 amino acids
Theoretical weight: 16.55 KDa
Source organism: Sindbis virus
UniProt:
Length: 151 amino acids
Theoretical weight: 16.55 KDa
Source organism: Sindbis virus
UniProt:
- Canonical: P03316 (Residues: 114-264; Coverage: 12%)
