Function and Biology Details
Reaction catalysed:
Cleavage of peptide bonds with very broad specificity.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Nucleophile aminohydrolases, N-terminal
- Proteasome B-type subunit
- Proteasome, subunit alpha/beta
- Peptidase T1A, proteasome beta-subunit
- Proteasome beta-type subunit, conserved site
- Proteasome alpha-subunit, N-terminal domain
- Proteasome activator PA28, C-terminal domain
- Proteasome activator superfamily
8 more domains
Structure domain:
Structure analysis Details
Assembly composition:
hetero 42-mer (preferred)
Assembly name:
Proteasome complex (preferred)
PDBe Complex ID:
PDB-CPX-149189 (preferred)
Entry contents:
15 distinct polypeptide molecules
Macromolecules (15 distinct):
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-1
Spacegroup:
P212121
Expression systems:
- Saccharomyces cerevisiae
- Escherichia coli