› 1z2e

Solution NMR

Solution Structure of Bacillus subtilis ArsC in oxidized state

Released:
DOI: 10.2210/pdb1z2e/pdb
PDB entry 1z2e coloured by chain, ensemble of 20 models, front view.
PDB entry 1z2e coloured by chain, ensemble of 20 models, side view.
PDB entry 1z2e coloured by chain, ensemble of 20 models, top view.
Source organism: Bacillus subtilis
Primary publication:
Solution structures and backbone dynamics of arsenate reductase from Bacillus subtilis: reversible conformational switch associated with arsenate reduction.
Guo X, Li Y, Peng K, Hu Y, Li C, Xia B, Jin C
J Biol Chem 280 39601-8 (2005)
PMID: 16192272

Function and Biology Details

Reaction catalysed: 
Arsenate + thioredoxin = arsenite + thioredoxin disulfide + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155369 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arsenate reductase Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.61 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli
UniProt:
  • Canonical: P45947 (Residues: 1-139; Coverage: 100%)
Gene names: BSU25780, arsC, yqcM
Sequence domains: Low molecular weight phosphotyrosine protein phosphatase
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction.
Tonks NK. (2013)
1 more

3 mentions without citation

How thioredoxin dissociates its mixed disulfide.
Roos et al. (2009)
2 more