› 1wwh

X-ray diffraction
2.7Å resolution

Crystal structure of the MPPN domain of mouse Nup35

Released:
DOI: 10.2210/pdb1wwh/pdb
PDB entry 1wwh coloured by chain, front view.
PDB entry 1wwh coloured by chain, side view.
PDB entry 1wwh coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The crystal structure of mouse Nup35 reveals atypical RNP motifs and novel homodimerization of the RRM domain.
Handa N, Kukimoto-Niino M, Akasaka R, Kishishita S, Murayama K, Terada T, Inoue M, Kigawa T, Kose S, Imamoto N, Tanaka A, Hayashizaki Y, Shirouzu M, Yokoyama S
J Mol Biol 363 114-24 (2006)
PMID: 16962612

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP35 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 119 amino acids
Theoretical weight: 12.91 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8R4R6 (Residues: 156-261; Coverage: 33%)
Gene names: Mp44, Nup35, Nup53
Sequence domains: Nup53/35/40-type RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P212121
Unit cell:
a: 59.486Å b: 104.237Å c: 110.039Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.234
Expression system: Not provided

Quick links

Citations

13 review citations

RNA recognition motifs: boring? Not quite.
Cléry et al. (2008)
12 more

3 mentions without citation

The Structure Inventory of the Nuclear Pore Complex.
Schwartz TU. (2016)
2 more