Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
SMAD2-SMAD4 complex (preferred)
PDBe Complex ID:
PDB-CPX-171712 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog 2
Molecule details ›
Chains: A, C
Length: 198 amino acids
Theoretical weight: 22.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Length: 198 amino acids
Theoretical weight: 22.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15796 (Residues: 270-467; Coverage: 42%)
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Mothers against decapentaplegic homolog 4
Molecule details ›
Chain: B
Length: 236 amino acids
Theoretical weight: 25.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Length: 236 amino acids
Theoretical weight: 25.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q13485 (Residues: 314-549; Coverage: 43%)
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
