› 1u2h

X-ray diffraction
0.96Å resolution

X-ray Structure of the N-terminally truncated human APEP-1

Released:
DOI: 10.2210/pdb1u2h/pdb
PDB entry 1u2h coloured by chain, front view.
PDB entry 1u2h coloured by chain, side view.
PDB entry 1u2h coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1).
Manjasetty BA, Niesen FH, Scheich C, Roske Y, Goetz F, Behlke J, Sievert V, Heinemann U, Büssow K
BMC Struct Biol 5 21 (2005)
PMID: 16354304

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172394 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Striated muscle preferentially expressed protein kinase Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 11.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15772 (Residues: 864-960; Coverage: 3%)
Gene names: APEG1, KIAA1297, SPEG
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: C2
Unit cell:
a: 81.541Å b: 25.522Å c: 42.544Å
α: 90° β: 104.59° γ: 90°
R-values:
R R work R free
0.161 0.161 0.172
Expression system: Escherichia coli

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Citations

2 review citations

Smooth muscle: a stiff sculptor of epithelial shapes.
Jaslove et al. (2018)
1 more

11 mentions without citation

The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units.
Dattilo et al. (2007)
10 more