› 1tei

X-ray diffraction
2.7Å resolution

STRUCTURE OF CONCANAVALIN A COMPLEXED TO BETA-D-GLCNAC (1,2)ALPHA-D-MAN-(1,6)[BETA-D-GLCNAC(1,2)ALPHA-D-MAN (1,6)]ALPHA-D-MAN

Released:
DOI: 10.2210/pdb1tei/pdb
PDB entry 1tei coloured by chain, front view.
PDB entry 1tei coloured by chain, side view.
PDB entry 1tei coloured by chain, top view.
Source organism: Canavalia ensiformis
Primary publication:
Concanavalin A distorts the beta-GlcNAc-(1-->2)-Man linkage of beta-GlcNAc-(1-->2)-alpha-Man-(1-->3)-[beta-GlcNAc-(1-->2)-alpha-Man- (1-->6)]-Man upon binding.
Moothoo DN, Naismith JH
Glycobiology 8 173-81 (1998)
PMID: 9451027

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-136271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Concanavalin-A, 2nd part Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 237 amino acids
Theoretical weight: 25.62 KDa
Source organism: Canavalia ensiformis
UniProt:
  • Canonical: P02866 (Residues: 28-148; Coverage: 46%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN, NAG
Carbohydrate polymer
2 bound ligands:
Ligand MN 8 x MN
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 176.5Å b: 122.8Å c: 124.6Å
α: 90° β: 134.2° γ: 90°
R-values:
R R work R free
0.179 0.179 0.219

Quick links

Citations

4 review citations

Structure and conformation of complex carbohydrates of glycoproteins, glycolipids, and bacterial polysaccharides.
Bush et al. (1999)
3 more

4 mentions without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
3 more