› 1t5s

X-ray diffraction
2.6Å resolution

Structure of the (SR)Ca2+-ATPase Ca2-E1-AMPPCP form

Released:
DOI: 10.2210/pdb1t5s/pdb
PDB entry 1t5s coloured by chain, front view.
PDB entry 1t5s coloured by chain, side view.
PDB entry 1t5s coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Sørensen TL, Møller JV, Nissen P
Science 304 1672-5 (2004)
PMID: 15192230

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

4 bound ligands:
Ligand CA 2 x CA
Ligand MG 1 x MG
Ligand K 1 x K
Ligand ACP 1 x ACP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 162.439Å b: 76.259Å c: 151.164Å
α: 90° β: 108.7° γ: 90°
R-values:
R R work R free
0.243 0.242 0.285

Quick links

Citations

47 review citations

P-type ATPases.
Palmgren et al. (2011)
46 more

37 mentions without citation

Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase.
Gulick AM. (2009)
36 more