› 1t3k

Solution NMR

NMR structure of a CDC25-like dual-specificity tyrosine phosphatase of Arabidopsis thaliana

Released:
DOI: 10.2210/pdb1t3k/pdb
PDB entry 1t3k coloured by chain, ensemble of 20 models, front view.
PDB entry 1t3k coloured by chain, ensemble of 20 models, side view.
PDB entry 1t3k coloured by chain, ensemble of 20 models, top view.
Source organism: Arabidopsis thaliana
Primary publication:
A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana.
Landrieu I, da Costa M, De Veylder L, Dewitte F, Vandepoele K, Hassan S, Wieruszeski JM, Corellou F, Faure JD, Van Montagu M, Inzé D, Lippens G
Proc Natl Acad Sci U S A 101 13380-5 (2004)
PMID: 15329414

Function and Biology Details

Reactions catalysed: 
Arsenate + glutathione + glutaredoxin = arsenite + a glutaredoxin-glutathione disulfide + H(2)O
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dual specificity phosphatase Cdc25 Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 16.94 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8GY31 (Residues: 15-146; Coverage: 90%)
Gene names: ACR2, ASR, At5g03455, CDC25, F12E4_220, STR5
Sequence domains: Rhodanese-like domain
Structure domains: Rhodanese-like domain

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Cell cycle regulation in plant development.
Inzé et al. (2006)
14 more

4 mentions without citation

Protein structure database search and evolutionary classification.
Yang et al. (2006)
3 more