› 1sqy

X-ray diffraction
2.5Å resolution

Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5

Released:
DOI: 10.2210/pdb1sqy/pdb
PDB entry 1sqy coloured by chain, front view.
PDB entry 1sqy coloured by chain, side view.
PDB entry 1sqy coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vikram P, Prem Kumar R, Singh N, Kumar J, Ethayathulla AS, Sharma S, Kaur P, Singh TP

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 691 amino acids
Theoretical weight: 76.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02788 (Residues: 20-710; Coverage: 100%)
Gene names: GIG12, LF, LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand FE 2 x FE
Ligand CO3 2 x CO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 56.156Å b: 98.09Å c: 157.036Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.204 0.215

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