› 1rz4

X-ray diffraction
2.1Å resolution

Crystal Structure of Human eIF3k

Released:
DOI: 10.2210/pdb1rz4/pdb
PDB entry 1rz4 coloured by chain, front view.
PDB entry 1rz4 coloured by chain, side view.
PDB entry 1rz4 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human eIF3k, the first structure of eIF3 subunits.
Wei Z, Zhang P, Zhou Z, Cheng Z, Wan M, Gong W
J Biol Chem 279 34983-90 (2004)
PMID: 15180986

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-193663 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 3 subunit K Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 26.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBQ5 (Residues: 1-218; Coverage: 100%)
Gene names: ARG134, EIF3K, EIF3S12, HSPC029, MSTP001, PTD001
Sequence domains: CSN8/PSMD8/EIF3K family
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P21212
Unit cell:
a: 83.074Å b: 44.671Å c: 55.524Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.187 0.222
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The scanning mechanism of eukaryotic translation initiation.
Hinnebusch AG. (2014)
4 more

14 mentions without citation

Structure characterization of the 26S proteasome.
Kim et al. (2011)
13 more