Function and Biology Details
Reaction catalysed:
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Neuropeptide Y and Dipeptidyl peptidase 4 (preferred)
PDBe Complex ID:
PDB-CPX-151019 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Dipeptidyl peptidase 4
Molecule details ›
Chains: A, B, C, D
Length: 739 amino acids
Theoretical weight: 85.64 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 739 amino acids
Theoretical weight: 85.64 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P27487 (Residues: 39-766; Coverage: 95%)
Sequence domains:
Structure domains:
Neuropeptide Y
Molecule details ›
Chains: E, F, G, H
Length: 10 amino acids
Theoretical weight: 1.1 KDa
Source organism: Macaca mulatta
Expression system: Not provided
UniProt:
Length: 10 amino acids
Theoretical weight: 1.1 KDa
Source organism: Macaca mulatta
Expression system: Not provided
UniProt:
- Canonical: Q9XSW6 (Residues: 29-38; Coverage: 15%)
