› 1r5m

X-ray diffraction
1.55Å resolution

Crystal Structure Of The C-Terminal WD40 Domain Of Sif2

Released:
DOI: 10.2210/pdb1r5m/pdb
PDB entry 1r5m coloured by chain, front view.
PDB entry 1r5m coloured by chain, side view.
PDB entry 1r5m coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The structure of Sif2p, a WD repeat protein functioning in the SET3 corepressor complex.
Cerna D, Wilson DK
J Mol Biol 351 923-35 (2005)
PMID: 16051270

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SIR4-interacting protein SIF2 Chain: A
Molecule details ›
Chain: A
Length: 425 amino acids
Theoretical weight: 46.42 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P38262 (Residues: 113-535; Coverage: 79%)
Gene names: EMB1, SIF2, YBR0832, YBR103W
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P65
Unit cell:
a: 107.1Å b: 107.1Å c: 82.59Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.19 0.204
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Nuclear hormone receptor co-repressors: structure and function.
Watson et al. (2012)
4 more

4 mentions without citation

Molecular architecture of the 40S⋅eIF1⋅eIF3 translation initiation complex.
Erzberger et al. (2014)
3 more