› 1qvi

X-ray diffraction
2.54Å resolution

Crystal structure of scallop myosin S1 in the pre-power stroke state to 2.6 Angstrom resolution: flexibility and function in the head

Released:
DOI: 10.2210/pdb1qvi/pdb
PDB entry 1qvi coloured by chain, front view.
PDB entry 1qvi coloured by chain, side view.
PDB entry 1qvi coloured by chain, top view.
Source organism: Argopecten irradians
Primary publication:
Crystal structure of scallop Myosin s1 in the pre-power stroke state to 2.6 a resolution: flexibility and function in the head.
Gourinath S, Himmel DM, Brown JH, Reshetnikova L, Szent-Györgyi AG, Cohen C
Structure 11 1621-7 (2003)
PMID: 14656445

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139482 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Myosin heavy chain, striated muscle Chain: A
Molecule details ›
Chain: A
Length: 840 amino acids
Theoretical weight: 95.82 KDa
Source organism: Argopecten irradians
UniProt:
  • Canonical: P24733 (Residues: 1-840; Coverage: 43%)
Sequence domains:
Myosin regulatory light chain, striated adductor muscle Chain: Y
Molecule details ›
Chain: Y
Length: 156 amino acids
Theoretical weight: 17.56 KDa
Source organism: Argopecten irradians
UniProt:
  • Canonical: P13543 (Residues: 2-157; Coverage: 99%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Myosin essential light chain, striated adductor muscle Chain: Z
Molecule details ›
Chain: Z
Length: 156 amino acids
Theoretical weight: 17.64 KDa
Source organism: Argopecten irradians
UniProt:
  • Canonical: P07291 (Residues: 2-157; Coverage: 99%)
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

4 bound ligands:
Ligand MG 2 x MG
Ligand VO4 1 x VO4
Ligand ADP 1 x ADP
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21
Unit cell:
a: 51.375Å b: 285.623Å c: 59.831Å
α: 90° β: 114.5° γ: 90°
R-values:
R R work R free
0.223 0.212 0.266

Quick links

Citations

8 review citations

The power of vanadate in crystallographic investigations of phosphoryl transfer enzymes.
Davies et al. (2004)
7 more

55 mentions without citation

Three perspectives on the molecular basis of hypercontractility caused by hypertrophic cardiomyopathy mutations.
Spudich JA. (2019)
54 more