Function and Biology Details
Reactions catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148630 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-induced, double-stranded RNA-activated protein kinase
Molecule details ›
Chain: A
Length: 179 amino acids
Theoretical weight: 19.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain
Length: 179 amino acids
Theoretical weight: 19.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P19525 (Residues: 1-170; Coverage: 31%)
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
MODIFIED DG/SA PROTOCOL IN XPLOR
Expression system: Escherichia coli BL21(DE3)
