› 1qhd

X-ray diffraction
1.95Å resolution

CRYSTAL STRUCTURE OF VP6, THE MAJOR CAPSID PROTEIN OF GROUP A ROTAVIRUS

Released:
DOI: 10.2210/pdb1qhd/pdb
PDB entry 1qhd coloured by chain, front view.
PDB entry 1qhd coloured by chain, side view.
PDB entry 1qhd coloured by chain, top view.
Source organism: Bovine rotavirus strain RF
Primary publication:
Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion.
Mathieu M, Petitpas I, Navaza J, Lepault J, Kohli E, Pothier P, Prasad BV, Cohen J, Rey FA
EMBO J 20 1485-97 (2001)
PMID: 11285213

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137887 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Intermediate capsid protein VP6 Chain: A
Molecule details ›
Chain: A
Length: 398 amino acids
Theoretical weight: 44.91 KDa
Source organism: Bovine rotavirus strain RF
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P04509 (Residues: 1-397; Coverage: 100%)
Sequence domains: Rotavirus major capsid protein VP6
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand ZN 1 x ZN
Ligand CL 1 x CL
Ligand CA 5 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11, EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P4132
Unit cell:
a: 157.78Å b: 157.78Å c: 157.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 0.22
Expression system: Spodoptera frugiperda

Quick links

Citations

16 review citations

Structural insights into the coupling of virion assembly and rotavirus replication.
Trask et al. (2012)
15 more

33 mentions without citation

Principles of virus structural organization.
Prasad et al. (2012)
32 more