› 1p5s

X-ray diffraction
2.22Å resolution

STRUCTURE AND FUNCTION OF THE CALPONIN-HOMOLOGY DOMAIN OF AN IQGAP PROTEIN FROM SCHIZOSACCHAROMYCES POMBE

Released:
DOI: 10.2210/pdb1p5s/pdb
PDB entry 1p5s coloured by chain, front view.
PDB entry 1p5s coloured by chain, side view.
PDB entry 1p5s coloured by chain, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Structure, crystal packing and molecular dynamics of the calponin-homology domain of Schizosaccharomyces pombe Rng2.
Wang CH, Balasubramanian MK, Dokland T
Acta Crystallogr D Biol Crystallogr 60 1396-403 (2004)
PMID: 15272162

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126951 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras GTPase-activating-like protein rng2 Chain: A
Molecule details ›
Chain: A
Length: 203 amino acids
Theoretical weight: 22.63 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli
UniProt:
  • Canonical: O14188 (Residues: 1-190; Coverage: 13%)
Gene names: SPAC4F8.13c, rng2
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

1 bound ligand:
Ligand HG 4 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 30.884Å b: 68.666Å c: 35.309Å
α: 90° β: 102.51° γ: 90°
R-values:
R R work R free
0.199 0.197 0.246
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Role of Rho GTPases and Rho-GEFs in the regulation of cell shape and integrity in fission yeast.
García et al. (2006)
1 more

1 mention without citation

Crystallization and X-ray diffraction analysis of the CH domain of the cotton kinesin GhKCH2.
Qin et al. (2016)