› 1lnq

X-ray diffraction
3.3Å resolution

CRYSTAL STRUCTURE OF MTHK AT 3.3 A

Released:
DOI: 10.2210/pdb1lnq/pdb
PDB entry 1lnq coloured by chain, front view.
PDB entry 1lnq coloured by chain, side view.
PDB entry 1lnq coloured by chain, top view.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Crystal structure and mechanism of a calcium-gated potassium channel.
Jiang Y, Lee A, Chen J, Cadene M, Chait BT, MacKinnon R
Nature 417 515-22 (2002)
PMID: 12037559

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 336 amino acids
Theoretical weight: 37.36 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 1-336; Coverage: 100%)
Gene names: MTH_1520, mthK
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P61
Unit cell:
a: 137Å b: 137Å c: 373.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.301 0.301 0.318
Expression system: Escherichia coli

Quick links

Citations

180 review citations

Inwardly rectifying potassium channels: their structure, function, and physiological roles.
Hibino et al. (2010)
179 more

86 mentions without citation

Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.
Bahar et al. (2010)
85 more