1lde

X-ray diffraction
2.5Å resolution

HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED TO NADH AND N-FORMYL PIPERDINE

Released:
Source organism: Equus caballus
Primary publication:
Binding of formamides to liver alcohol dehydrogenase.
Biochemistry 36 3522-7 (1997)
PMID: 9132002

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-132405 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alcohol dehydrogenase E chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 374 amino acids
Theoretical weight: 39.85 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: P00327 (Residues: 2-375; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 4 x NAD
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P21
Unit cell:
a: 49.93Å b: 180.2Å c: 86.8Å
α: 90° β: 106° γ: 90°
R-values:
R R work R free
0.205 0.205 0.256