› 1kzx

Solution NMR

Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T)

Released:
DOI: 10.2210/pdb1kzx/pdb
PDB entry 1kzx coloured by chain, ensemble of 20 models, front view.
PDB entry 1kzx coloured by chain, ensemble of 20 models, side view.
PDB entry 1kzx coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism.
Zhang F, Lücke C, Baier LJ, Sacchettini JC, Hamilton JA
Biochemistry 42 7339-47 (2003)
PMID: 12809489

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146097 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, intestinal Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 15.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12104 (Residues: 2-132; Coverage: 99%)
Gene names: FABP2, FABPI
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing combined with torsion angle dynamics and followed by energy minimization
Expression system: Escherichia coli BL21(DE3)

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Citations

2 review citations

Structural and functional analysis of fatty acid-binding proteins.
Storch et al. (2009)
1 more