› 1k34

X-ray diffraction
1.88Å resolution

Crystal structure analysis of gp41 core mutant

Released:
DOI: 10.2210/pdb1k34/pdb
PDB entry 1k34 coloured by chain, front view.
PDB entry 1k34 coloured by chain, side view.
PDB entry 1k34 coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.
Wang S, York J, Shu W, Stoller MO, Nunberg JH, Lu M
Biochemistry 41 7283-92 (2002)
PMID: 12044159

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137976 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.84 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P04578 (Residues: 546-655; Coverage: 8%)
Gene name: env
Sequence domains: Retroviral envelope protein
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: R3
Unit cell:
a: 52.214Å b: 52.214Å c: 60.904Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 0.197 0.216
Expression system: Escherichia coli

Quick links

Citations

1 review citation

HIV-1 viral genes and mitochondrial apoptosis.
Shedlock et al. (2008)
30 other articles

2 mentions without citation

HIV-1 envelope glycoprotein structure.
Merk et al. (2013)
1 more