› 1jih

X-ray diffraction
2.25Å resolution

Function and Biology Details

Reaction catalysed: 
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169989 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase eta Chains: A, B
Molecule details ›
Chains: A, B
Length: 513 amino acids
Theoretical weight: 58.15 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q04049 (Residues: 1-513; Coverage: 81%)
Gene names: DBH1, RAD30, YDR419W
Sequence domains: impB/mucB/samB family
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID, NSLS BEAMLINE X4A
Spacegroup: P41212
Unit cell:
a: 105.1Å b: 105.1Å c: 292.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.215 0.245
Expression system: Saccharomyces cerevisiae

Quick links

Citations

44 review citations

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function.
Prakash et al. (2005)
43 more

11 mentions without citation

An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η.
Yang W. (2014)
10 more