› 1ivz

Solution NMR

Solution structure of the SEA domain from murine hypothetical protein homologous to human mucin 16

Released:
DOI: 10.2210/pdb1ivz/pdb
PDB entry 1ivz coloured by chain, ensemble of 20 models, front view.
PDB entry 1ivz coloured by chain, ensemble of 20 models, side view.
PDB entry 1ivz coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16).
Maeda T, Inoue M, Koshiba S, Yabuki T, Aoki M, Nunokawa E, Seki E, Matsuda T, Motoda Y, Kobayashi A, Hiroyasu F, Shirouzu M, Terada T, Hayami N, Ishizuka Y, Shinya N, Tatsuguchi A, Yoshida M, Hirota H, Matsuo Y, Tani K, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Kigawa T, Yokoyama S
J Biol Chem 279 13174-82 (2004)
PMID: 14764598

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190042 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SEA domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 14.67 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q9D1H1 (Residues: 65-185; Coverage: 47%)
Gene name: Muc16
Sequence domains: SEA domain
Structure domains: SEA domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Not provided

Quick links

Citations

13 review citations

Structure and function of the cell surface (tethered) mucins.
Hattrup et al. (2008)
12 more

5 mentions without citation

A valid mouse model of AGRIN-associated congenital myasthenic syndrome.
Bogdanik et al. (2011)
4 more