› 1ip0

Solution NMR

NMR STRUCTURE OF HUMAN BETACELLULIN-2

Released:
DOI: 10.2210/pdb1ip0/pdb
PDB entry 1ip0 coloured by chain, front view.
PDB entry 1ip0 coloured by chain, side view.
PDB entry 1ip0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of betacellulin, a new member of EGF-family ligands.
Miura K, Doura H, Aizawa T, Tada H, Seno M, Yamada H, Kawano K
Biochem Biophys Res Commun 294 1040-6 (2002)
PMID: 12074582

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Betacellulin Chain: A
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35070 (Residues: 62-111; Coverage: 34%)
Gene name: BTC
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesis.
Dreux et al. (2006)
1 more

2 mentions without citation

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals.
Eagles et al. (2022)
1 more