› 1gsm

X-ray diffraction
1.9Å resolution

A reassessment of the MAdCAM-1 structure and its role in integrin recognition.

Released:
DOI: 10.2210/pdb1gsm/pdb
PDB entry 1gsm coloured by chain, front view.
PDB entry 1gsm coloured by chain, side view.
PDB entry 1gsm coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A reassessment of the MAdCAM-1 structure and its role in integrin recognition.
Dando J, Wilkinson KW, Ortlepp S, King DJ, Brady RL
Acta Crystallogr D Biol Crystallogr 58 233-41 (2002)
PMID: 11807247

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171707 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mucosal addressin cell adhesion molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 210 amino acids
Theoretical weight: 22.29 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: Q13477 (Residues: 19-224; Coverage: 57%)
Gene name: MADCAM1
Sequence domains: Adhesion molecule, immunoglobulin-like
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2221
Unit cell:
a: 64Å b: 99.2Å c: 70.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.217 0.25
Expression system: Mus musculus

Quick links

Citations

1 review citation

Structural basis for ligand recognition by integrins.
Takagi J. (2007)
7 other articles

7 mentions without citation

The receptor for advanced glycation end-products (RAGE) is only present in mammals, and belongs to a family of cell adhesion molecules (CAMs).
Sessa et al. (2014)
6 more