› 1g6h

X-ray diffraction
1.6Å resolution

CRYSTAL STRUCTURE OF THE ADP CONFORMATION OF MJ1267, AN ATP-BINDING CASSETTE OF AN ABC TRANSPORTER

Released:
DOI: 10.2210/pdb1g6h/pdb
PDB entry 1g6h coloured by chain, front view.
PDB entry 1g6h coloured by chain, side view.
PDB entry 1g6h coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii
Primary publication:
Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter.
Karpowich N, Martsinkevich O, Millen L, Yuan YR, Dai PL, MacVey K, Thomas PJ, Hunt JF
Structure 9 571-86 (2001)
PMID: 11470432

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176672 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Probable branched-chain amino acid transport ATP-binding protein LivG Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 29.02 KDa
Source organism: Methanocaldococcus jannaschii
UniProt:
  • Canonical: Q58663 (Residues: 1-257; Coverage: 100%)
Gene names: MJ1267, livG
Sequence domains: ABC transporter
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
Ligand MG 1 x MG
Ligand MMC 1 x MMC
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 107.807Å b: 60.463Å c: 42.73Å
α: 90° β: 92.16° γ: 90°
R-values:
R R work R free
0.217 0.217 0.252

Quick links

Citations

59 review citations

Siderophore-based iron acquisition and pathogen control.
Miethke et al. (2007)
58 more

8 mentions without citation

Mechanism of ABC transporters: a molecular dynamics simulation of a well characterized nucleotide-binding subunit.
Jones et al. (2002)
7 more