› 1g2t

Solution NMR

SOLUTION STRUCTURE OF EOTAXIN-3

Released:
DOI: 10.2210/pdb1g2t/pdb
PDB entry 1g2t coloured by chain, ensemble of 20 models, front view.
PDB entry 1g2t coloured by chain, ensemble of 20 models, side view.
PDB entry 1g2t coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR solution structure and backbone dynamics of the CC chemokine eotaxin-3.
Ye J, Mayer KL, Mayer MR, Stone MJ
Biochemistry 40 7820-31 (2001)
PMID: 11425309

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195102 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-C motif chemokine 26 Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 8.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y258 (Residues: 24-94; Coverage: 100%)
Gene names: CCL26, SCYA26, UNQ216/PRO242
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry-simulated annealing protocol implemented in XPLOR
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Eosinophils in mucosal immune responses.
Travers et al. (2015)
2 more

3 mentions without citation

The marriage of chemokines and galectins as functional heterodimers.
von Hundelshausen et al. (2021)
2 more