› 1g0x

X-ray diffraction
2.1Å resolution

CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2)

Released:
DOI: 10.2210/pdb1g0x/pdb
PDB entry 1g0x coloured by chain, front view.
PDB entry 1g0x coloured by chain, side view.
PDB entry 1g0x coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2).
Chapman TL, Heikema AP, West AP, Bjorkman PJ
Immunity 13 727-36 (2000)
PMID: 11114384

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185548 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocyte immunoglobulin-like receptor subfamily B member 1 Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8NHL6 (Residues: 25-221; Coverage: 31%)
Gene names: ILT2, LILRB1, LIR1, MIR7
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P41212
Unit cell:
a: 68.258Å b: 68.258Å c: 129.734Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.244
Expression system: Escherichia coli

Quick links

Citations

28 review citations

Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.
Natarajan et al. (2002)
27 more

11 mentions without citation

Global dynamics of proteins: bridging between structure and function.
Bahar et al. (2010)
10 more