Function and Biology Details
Reactions catalysed:
Testosterone + NAD(P)(+) = androst-4-ene-3,17-dione + NAD(P)H
17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
17-beta-hydroxysteroid dehydrogenase type 1 (preferred)
PDBe Complex ID:
PDB-CPX-146840 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
17-beta-hydroxysteroid dehydrogenase type 1
Molecule details ›
Chains: A, B, C, D
Length: 327 amino acids
Theoretical weight: 34.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain
Length: 327 amino acids
Theoretical weight: 34.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P14061 (Residues: 2-328; Coverage: 100%)
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain
