› 1fbm

X-ray diffraction
2.7Å resolution

ASSEMBLY DOMAIN OF CARTILAGE OLIGOMERIC MATRIX PROTEIN IN COMPLEX WITH ALL-TRANS RETINOL

Released:
DOI: 10.2210/pdb1fbm/pdb
PDB entry 1fbm coloured by chain, front view.
PDB entry 1fbm coloured by chain, side view.
PDB entry 1fbm coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
All-trans retinol, vitamin D and other hydrophobic compounds bind in the axial pore of the five-stranded coiled-coil domain of cartilage oligomeric matrix protein.
Guo Y, Bozic D, Malashkevich VN, Kammerer RA, Schulthess T, Engel J
EMBO J 17 5265-72 (1998)
PMID: 9736606

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152922 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cartilage oligomeric matrix protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 46 amino acids
Theoretical weight: 5.3 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P35444 (Residues: 27-72; Coverage: 6%)
Gene name: Comp
Sequence domains: Cartilage oligomeric matrix protein
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand RTL 1 x RTL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-20
Spacegroup: P21
Unit cell:
a: 38.47Å b: 49.47Å c: 54.98Å
α: 90° β: 103.84° γ: 90°
R-values:
R R work R free
0.195 0.195 not available
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

The thrombospondins.
Adams et al. (2004)
10 more

4 mentions without citation

Classification of intrinsically disordered regions and proteins.
van der Lee et al. (2014)
3 more