› 1ek0

X-ray diffraction
1.48Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153102 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolar protein sorting-associated protein 21 Chain: A
Molecule details ›
Chain: A
Length: 170 amino acids
Theoretical weight: 18.96 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P36017 (Residues: 5-174; Coverage: 81%)
Gene names: VPS12, VPS21, VPT12, YOR089C, YOR3154C, YPT21, YPT51
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

4 bound ligands:
Ligand MG 1 x MG
Ligand NI 1 x NI
Ligand GNP 1 x GNP
Ligand GDP 1 x GDP
1 modified residue:
Ligand MHO 2 x MHO

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P61
Unit cell:
a: 62.326Å b: 62.326Å c: 91.221Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.228
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

The Rab GTPase family.
Stenmark et al. (2001)
5 more

7 mentions without citation

Structural mechanisms for regulation of membrane traffic by rab GTPases.
Lee et al. (2009)
6 more