› 1dsb

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF THE DSBA PROTEIN REQUIRED FOR DISULPHIDE BOND FORMATION IN VIVO

Released:
DOI: 10.2210/pdb1dsb/pdb
PDB entry 1dsb coloured by chain, front view.
PDB entry 1dsb coloured by chain, side view.
PDB entry 1dsb coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of the DsbA protein required for disulphide bond formation in vivo.
Martin JL, Bardwell JC, Kuriyan J
Nature 365 464-8 (1993)
PMID: 8413591

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142452 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thiol:disulfide interchange protein DsbA Chains: A, B
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 21.16 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P0AEG4 (Residues: 20-208; Coverage: 100%)
Gene names: JW3832, b3860, dsbA, dsf, ppfA
Sequence domains: DSBA-like thioredoxin domain
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 117.5Å b: 65Å c: 76.5Å
α: 90° β: 126.3° γ: 90°
R-values:
R R work R free
0.169 0.169 not available
Expression system: Not provided

Quick links

Citations

76 review citations

Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily.
Sheehan et al. (2001)
75 more

14 mentions without citation

Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase.
Cheng et al. (2011)
13 more