› 1d6t

Solution NMR

RNASE P PROTEIN FROM STAPHYLOCOCCUS AUREUS

Released:
DOI: 10.2210/pdb1d6t/pdb
PDB entry 1d6t coloured by chain, ensemble of 20 models, front view.
PDB entry 1d6t coloured by chain, ensemble of 20 models, side view.
PDB entry 1d6t coloured by chain, ensemble of 20 models, top view.
Source organism: Staphylococcus aureus
Primary publication:
The structure of ribonuclease P protein from Staphylococcus aureus reveals a unique binding site for single-stranded RNA.
Spitzfaden C, Nicholson N, Jones JJ, Guth S, Lehr R, Prescott CD, Hegg LA, Eggleston DS
J Mol Biol 295 105-15 (2000)
PMID: 10623511

Function and Biology Details

Reaction catalysed: 
Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140928 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease P protein component Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.68 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0A0H5 (Residues: 1-117; Coverage: 100%)
Gene name: rnpA
Sequence domains: Ribonuclease P
Structure domains: Ribosomal Protein S5; domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli BL21

Quick links

Citations

16 review citations

RNase P: interface of the RNA and protein worlds.
Evans et al. (2006)
15 more

4 mentions without citation

Of proteins and RNA: the RNase P/MRP family.
Esakova et al. (2010)
3 more