› 1c4p

X-ray diffraction
2.4Å resolution

BETA DOMAIN OF STREPTOKINASE

Released:
DOI: 10.2210/pdb1c4p/pdb
PDB entry 1c4p coloured by chain, front view.
PDB entry 1c4p coloured by chain, side view.
PDB entry 1c4p coloured by chain, top view.
Source organism: Streptococcus dysgalactiae subsp. equisimilis
Primary publication:
Crystal structure of streptokinase beta-domain.
Wang X, Tang J, Hunter B, Zhang XC
FEBS Lett 459 85-9 (1999)
PMID: 10508922

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SKC-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 137 amino acids
Theoretical weight: 15.83 KDa
Source organism: Streptococcus dysgalactiae subsp. equisimilis
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q53284 (Residues: 149-285; Coverage: 33%)
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 73.97Å b: 83.99Å c: 97.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.237 0.304
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

Streptokinase--a clinically useful thrombolytic agent.
Banerjee et al. (2004)
1 more

6 mentions without citation

Understanding biology by stretching proteins: recent progress.
Galera-Prat et al. (2010)
5 more