› 1bmo

X-ray diffraction
3.1Å resolution

BM-40, FS/EC DOMAIN PAIR

Released:
DOI: 10.2210/pdb1bmo/pdb
PDB entry 1bmo coloured by chain, front view.
PDB entry 1bmo coloured by chain, side view.
PDB entry 1bmo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40.
Hohenester E, Maurer P, Timpl R
EMBO J 16 3778-86 (1997)
PMID: 9233787

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140673 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
SPARC Chains: A, B
Molecule details ›
Chains: A, B
Length: 233 amino acids
Theoretical weight: 27.11 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P09486 (Residues: 71-303; Coverage: 82%)
Gene names: ON, SPARC
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-21
Spacegroup: P21
Unit cell:
a: 70.77Å b: 56.35Å c: 111.6Å
α: 90° β: 104.38° γ: 90°
R-values:
R R work R free
0.262 0.262 0.322
Expression system: Homo sapiens

Quick links

Citations

18 review citations

Matricellular proteins: extracellular modulators of cell function.
Bornstein et al. (2002)
17 more

17 mentions without citation

Dissecting the conformation of glycans and their interactions with proteins.
Wang et al. (2020)
16 more