Function and Biology Details
Reactions catalysed:
Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.
Release of N-terminal proline from a peptide.
An (L-cysteinylglycine)-S-conjugate + H(2)O = an L-cysteine-S-conjugate + glycine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
Cytosol aminopeptidase and peptide (preferred)
PDBe Complex ID:
PDB-CPX-133041 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cytosol aminopeptidase
Molecule details ›
Chain: E
Length: 488 amino acids
Theoretical weight: 52.97 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
Sequence domains:
Structure domains:
Length: 488 amino acids
Theoretical weight: 52.97 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
- Canonical:
P00727 (Residues: 33-519; Coverage: 94%)
Sequence domains:
Structure domains:
