› 1b8q

Solution NMR

SOLUTION STRUCTURE OF THE EXTENDED NEURONAL NITRIC OXIDE SYNTHASE PDZ DOMAIN COMPLEXED WITH AN ASSOCIATED PEPTIDE

Released:
DOI: 10.2210/pdb1b8q/pdb
PDB entry 1b8q coloured by chain, ensemble of 15 models, front view.
PDB entry 1b8q coloured by chain, ensemble of 15 models, side view.
PDB entry 1b8q coloured by chain, ensemble of 15 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide.
Tochio H, Zhang Q, Mandal P, Li M, Zhang M
Nat Struct Biol 6 417-21 (1999)
PMID: 10331866

Function and Biology Details

Reaction catalysed: 
(1a) 2 L-arginine + 2 NADPH + 2 O(2) = 2 N(omega)-hydroxy-L-arginine + 2 NADP(+) + 2 H(2)O
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151518 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nitric oxide synthase 1 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 13.55 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P29476 (Residues: 7-133; Coverage: 9%)
Gene names: Bnos, Nos1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
PROTEIN (HEPTAPEPTIDE) Chain: B
Molecule details ›
Chain: B
Length: 7 amino acids
Theoretical weight: 746 Da
Source organism: Rattus norvegicus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

15 review citations

PDZ domains and the organization of supramolecular complexes.
Sheng et al. (2001)
14 more

7 mentions without citation

Specificity in PDZ-peptide interaction networks: Computational analysis and review.
Amacher et al. (2020)
6 more