› 1an0

X-ray diffraction
2.8Å resolution

CDC42HS-GDP COMPLEX

Released:
DOI: 10.2210/pdb1an0/pdb
PDB entry 1an0 coloured by chain, front view.
PDB entry 1an0 coloured by chain, side view.
PDB entry 1an0 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kongsaeree P, Cerione R, Clardy J

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division control protein 42 homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 190 amino acids
Theoretical weight: 21.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P60953 (Residues: 1-190; Coverage: 100%)
Gene name: CDC42
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand GDP 2 x GDP
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P41212
Unit cell:
a: 99.44Å b: 99.44Å c: 102.67Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.344
Expression system: Escherichia coli

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